The Sinclair Method uses naltrexone, taken before drinking, to gradually reduce the pull of alcohol. Doctor-led, evidence-based, no abstinence required to start. Your price is confirmed at your assessment. Pause or cancel any time.
Doctor-led | No judgement | One visit or ongoing
If you are on this medication from another clinic, an NHS service, or an online provider, and you want to move your care to us, you are very welcome. Bring whatever records you have and we will take it from there. No obligation to switch onto a subscription.
A simple, evidence-based protocol.
A 10-minute online consultation form covers your drinking history (using the AUDIT questionnaire), medical history, and the contraindications we need to screen for. No judgement, no assumptions.
A doctor on the GMC GP Register reviews your assessment within one working day and discusses naltrexone with you on a video or phone consultation. If treatment is right, we prescribe and dispense.
An hour before any drinking, every time. Skip it on alcohol-free days. Most people find their consumption falls within 4 to 12 weeks; the original Finnish trials showed 78% reaching safe-drinking levels over 6 to 12 months.
Your monthly subscription bundles the medication and the clinical service.
Your prescribed naltrexone, dispensed by our pharmacy and delivered in plain packaging.
An initial assessment, then a clinical review every month.
Tuning as you respond. Most people stay on a standard dose; some need adjustment.
Message the clinical team between reviews. Most messages answered within one working day.
Plain-packaged, free delivery anywhere in the UK. No name on the box.
No exit fee. Take a break and come back, or stop entirely.
The Sinclair Method works best for people who want to drink less but don't necessarily want to abstain entirely. The original Finnish trials reported 78% of participants reaching safe-drinking levels over 6 to 12 months.
If you're using opioid pain medication, have severe liver disease, are pregnant, or have certain other contraindications, naltrexone isn't appropriate. The assessment will identify these. We won't prescribe and we'll talk you through alternatives.
Naltrexone blocks the brain's opioid receptors, which is the pathway alcohol uses to reinforce itself. Taken about an hour before drinking, naltrexone gradually reduces the reward loop: drinking still happens, but the pull to drink the next one weakens over weeks and months.
The protocol is simple: take naltrexone before any drinking, every time. Skip it on alcohol-free days. The treatment runs for as long as it's working, with monthly reviews so the doctor can fine-tune the dose and check on side effects.
The Sinclair Method does not require abstinence to begin. You don't have to commit to stopping; you commit to a method that, over time, makes drinking less feel natural rather than effortful.
Most people see us in one of three ways. Pick the one that suits where you are.
Once. Book a single consultation. We assess you, prescribe if appropriate, dispense, and you are on your way. No subscription, no follow-up, nothing else to commit to. If you want to come back, you book again when you need to.
Already on treatment. If you are already taking this medication from somewhere else and want to move your care to us, you are very welcome. Bring whatever records you have and we will take it from there. There is no obligation to switch to a subscription — you can stay on whatever cadence suits you.
Ongoing care. If you would rather we look after this in the background, a monthly subscription bundles your medication and reviews into one regular payment. Pause or cancel when you like. We do not charge an exit fee. Most people on subscription started with a one-off and decided they wanted us to take it off their plate.
Your monthly subscription covers the clinical service: assessment, monthly doctor reviews, dose changes, messaging, and delivery. Naltrexone is included in the subscription price.
Sinclair Method subscription (clinical service plus naltrexone): price confirmed at your assessment
Bloods (where clinically needed): priced individually or included in your nearest blood test package
Pause or cancel any time. No exit charge.
Subscription clients can book in-person appointments at our Westfield London clinic, included in the monthly fee. Many people prefer to do their first consultation in person; others stay online once treatment is settled.
Your monthly reviews run by secure video or phone. Or in person at our Westfield London clinic if you would rather.

Want to read more before you book? Start with these.
Drink less without abstinence, using naltrexone.
Explore: The Sinclair MethodWhat to expect.
Explore: First 14 days on TSMA realistic timeline.
Explore: How long does TSM takeWhat is common, what is rare.
Explore: Naltrexone side effectsThe choice between two options.
Explore: Naltrexone vs nalmefeneAre they compatible?
Explore: The Sinclair Method and AA