Practicalities
How much does naltrexone cost in the UK?
A breakdown of what you'll actually pay for naltrexone privately in the UK, including which providers charge what and where the costs come from.
Dr Seth Rankin
MBChB MRCGP, GMC 4467397
19 April 2026
5 min read
Naltrexone is a prescription medication used in the Sinclair Method to reduce problem drinking. In the UK, it is rarely prescribed on the NHS for this indication, so almost all patients pay privately. There are two costs to think about: the medication itself, and the clinical service that gets you the prescription.
The medication
A pack of 28 naltrexone 50mg tablets retails between £85 and £100 from UK private pharmacies in 2026. The exact price varies by pharmacy, brand, and supply availability.
Sinclair Method UK Ltd's specialist pharmacy: £89-99 per 28 tablets
Rethink Drink's pharmacy: £85 per 28 tablets
ChooseNUL: medication included in their £199/month subscription
LoveMyLife in-house pharmacy: £99/pack retail or £79/pack at member rate (Programme/Ongoing tiers)
How long a pack lasts depends entirely on how often you drink. The protocol is one tablet per drinking occasion, so a regular daily drinker uses about a pack a month, while someone who drinks two or three days a week uses a pack every six to eight weeks.
The clinical service
UK private providers structure the clinical service in different ways:
LoveMyLife — four tiers from £99 (form-reviewed prescription) to £499 (90-day doctor-led, nurse-delivered programme)
Sinclair Method UK Ltd — £595 for a 12-week programme or £795 for 5 months, one-off, medication separate
ChooseNUL — £50 suitability assessment, then £199/month subscription with medication included (3-month minimum)
Rethink Drink — coaching-led 90-day programme, pricing available on signup
Total typical cost for a 90-day programme
Adding service fee plus medication, total cost varies a lot by provider:
LoveMyLife Direct + 1 pack: ~£198
LoveMyLife Programme + 3-pack medication: ~£740
Sinclair Method UK 12-week + 3 packs: ~£860-892
ChooseNUL 3-month subscription + setup: £647
Rethink Drink: ~£600-800 + ~£255 medication
What about the cost of bloods?
Most providers recommend a baseline liver function test (LFT). At LoveMyLife our LFT is £49 via our own lab, or you can bring a recent NHS LFT for free. Other providers' bloods range from £49 to £73. Some, including LoveMyLife and TSMUK, allow patients to start without an LFT initially if their history is low-risk.
For a full breakdown of LoveMyLife's tier costs and what's included, see our pricing page.
Clinically reviewed
Dr Seth Rankin · MBChB MRCGP, GMC 4467397
Last reviewed on 19 April 2026
Next review due 19 April 2027
Reviewed by the LoveMyLife clinical team
Read next
More from our Sinclair Method articles.
3 services
What is the Sinclair Method?
A short, plain-English explanation of how naltrexone, taken before drinking, changes a patient's relationsh...
Naltrexone vs nalmefene: which is right for you?
Both are opioid antagonists used in the Sinclair Method. The differences (licensing, liver effects, dosing,...
The Sinclair Method on the NHS: what's available?
Why the NHS rarely prescribes naltrexone for TSM, and what your options are if you can't afford private.
Explore the full Sinclair Method
Different parts of the story live on different pages. Open whichever is most useful to you.
6 services
Service overview
The main service page — overview, pricing summary, and how our four tiers work.
Pricing in depth
Four tiers from £99, all-inclusive. Compare each tier side by side with a feature ticklist.
The science
Pharmacological extinction, explained clearly — how naltrexone works on the brain's reward system.
Is the Sinclair Method right for me?
Five honest questions to work out whether the Sinclair Method is the right approach for you.
Frequently asked questions
Thirty-plus questions answered in plain English, grouped by theme.
How we compare to other UK providers
Side by side with the other UK Sinclair Method providers — what each of us offers, honestly.
Ready to start?
The consultation form takes 15-20 minutes. We confirm your tier and next steps within 24 hours.